Long lasting pure freezing of gait preceding progressive supranuclear palsy: A clinicopathological study
Identifieur interne : 002D68 ( Main/Exploration ); précédent : 002D67; suivant : 002D69Long lasting pure freezing of gait preceding progressive supranuclear palsy: A clinicopathological study
Auteurs : Yaroslau Compta [Espagne] ; Francesc Valldeoriola [Espagne] ; Eduardo Tolosa [Espagne] ; María Jesús Rey [Espagne] ; María José Martí [Espagne] ; Josep Valls-Solé [Espagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-10-15.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Congélation.
English descriptors
- KwdEn :
- Accidental Falls, Aged, Astrocytes (pathology), Brain (pathology), Diagnosis, Differential, Disease Progression, Dopamine Plasma Membrane Transport Proteins (physiology), Female, Freezing, Gait Disorders, Neurologic (diagnosis), Gait Disorders, Neurologic (pathology), Gait disorder, Humans, Inclusion Bodies (pathology), Iodine Radioisotopes (diagnostic use), Long lasting, Magnetic Resonance Imaging, Nervous system diseases, Neurofibrillary Tangles (pathology), Neurologic Examination, Neuropil (pathology), Nortropanes (diagnostic use), Oligodendroglia (pathology), Supranuclear Palsy, Progressive (diagnosis), Supranuclear Palsy, Progressive (pathology), Tauopathies (diagnosis), Tauopathies (pathology), Tomography, Emission-Computed, Single-Photon, gait disorders, progressive supranuclear palsy, pure freezing of gait.
- MESH :
- chemical , diagnostic use : Iodine Radioisotopes, Nortropanes.
- chemical , physiology : Dopamine Plasma Membrane Transport Proteins.
- diagnosis : Gait Disorders, Neurologic, Supranuclear Palsy, Progressive, Tauopathies.
- pathology : Astrocytes, Brain, Gait Disorders, Neurologic, Inclusion Bodies, Neurofibrillary Tangles, Neuropil, Oligodendroglia, Supranuclear Palsy, Progressive, Tauopathies.
- Accidental Falls, Aged, Diagnosis, Differential, Disease Progression, Female, Humans, Magnetic Resonance Imaging, Neurologic Examination, Tomography, Emission-Computed, Single-Photon.
Abstract
Primary progressive freezing of gait (PPFG) is the term used to designate an uncommon condition featuring freezing of gait with frequent falls, without bradykinesia, rigidity or tremor, and unresponsive to levodopa. There are very few pathological reports of patients with PPFG in the literature. We report on 2 patients (one with pathological confirmation) diagnosed initially as PPFG and evolving into clinically defined progressive supranuclear palsy (PSP) more than 10 years after onset of symptoms. These 2 cases suggest that PPFG can represent the initial manifestation of a neurodegenerative disease, such as PSP, rather than a differentiated nosological entity. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21612
Affiliations:
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Le document en format XML
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There are very few pathological reports of patients with PPFG in the literature. We report on 2 patients (one with pathological confirmation) diagnosed initially as PPFG and evolving into clinically defined progressive supranuclear palsy (PSP) more than 10 years after onset of symptoms. These 2 cases suggest that PPFG can represent the initial manifestation of a neurodegenerative disease, such as PSP, rather than a differentiated nosological entity. © 2007 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Espagne</li></country></list><tree><country name="Espagne"><noRegion><name sortKey="Compta, Yaroslau" sort="Compta, Yaroslau" uniqKey="Compta Y" first="Yaroslau" last="Compta">Yaroslau Compta</name></noRegion><name sortKey="Marti, Maria Jose" sort="Marti, Maria Jose" uniqKey="Marti M" first="María José" last="Martí">María José Martí</name><name sortKey="Rey, Maria Jesus" sort="Rey, Maria Jesus" uniqKey="Rey M" first="María Jesús" last="Rey">María Jesús Rey</name><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name><name sortKey="Valldeoriola, Francesc" sort="Valldeoriola, Francesc" uniqKey="Valldeoriola F" first="Francesc" last="Valldeoriola">Francesc Valldeoriola</name><name sortKey="Valls Ole, Josep" sort="Valls Ole, Josep" uniqKey="Valls Ole J" first="Josep" last="Valls-Solé">Josep Valls-Solé</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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